脊髓损伤神经修复药物KCL-286通过1期临床试验

在2023年7月15日出版的《British journal of clinical pharmacology》上，Corcoran的研发团队发表了KCL-286的健康人群1期临床试验结果，初步验证KCL-286的耐受性良好，主要的不反应为皮肤干燥、皮…

发布时间：2023-07-15浏览数：611

Donanemab in Early Alzheimer's Disease

In patients with early Alzheimer's disease, donanemab resulted in a better composite score for cognition and for the ability to perform activities of daily living than placebo at 76…

发布时间：2021-05-06浏览数：554

Donanemab (LY3002813) dose-escalation study in Alzheimer's disease

Intravenous donanemab 10 mg/kg can reduce amyloid deposits in AD despite having a shorter than expected half-life.

发布时间：2021-02-14浏览数：657

A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice

These studies have profound implications for the development of therapeutic Aβ antibodies for Alzheimer's disease.

发布时间：2012-01-06浏览数：645

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques

A beta N3(pE) production and retention may play an early and critical role in senile plaque formation.

发布时间：1995-02-01浏览数：568